Evaluation of Marker Enzymes in Fibroid Patients

Marker enzymes such as acid phosphatase(ACP), alkaline phosphatase(ALP) and aspartate transaminase(AST) levels were estimated in the serum of 60 fibroid patients and 60 non-fibroid patients from UTH, Ado-Ekiti . The age, weight and height of the patients were also considered. Results obtained showed a significant increase in the level of ACP (12.15±6.02μ/L), significant decrease in AST (10.24±3.10μ/L) level, and no significant difference was recorded in ALP (14.99±2.20μ/L) level when compared to the control (10.10±6.15μ/L), (12.40±3.11μ/L) and (15.52±1.30μ/L) respectively. Significant increase in both the age and weight of fibroid patients were also observed which could be related to the etiology of fibroid while height (not significant) may not be related to fibroid. However, this study showed that the activity of ALP does not change in fibroid cases while there are changes in the activities of both ACP and AST.